Peer-reviewed veterinary case report
Pekingese dog with seizures and smooth brain diagnosed by MRI
By Shimbo, Genya et al.·Published in The Journal of veterinary medical science·2017·Obihiro University of Agriculture and Veterinary Medicine, Japan·View original on PubMed →
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Original publication title: Lissencephaly in a Pekingese.
- Species:
- dog
Plain-English summary
A 1-year-old neutered male Pekingese was brought in because he was having cluster seizures and showing unusual behavior. After a thorough examination and an MRI, the vet discovered that the dog's brain had a smooth surface instead of the usual folds, which is a condition called lissencephaly. He also had a cyst in his brain. To manage his seizures, the vet prescribed high doses of multiple anticonvulsant medications, which helped control the seizures.
People also search for: Pekingese seizures treatment · dog brain problems · lissencephaly in dogs · puppy seizure medication
Abstract
A 1-year-old neutered male Pekingese was presented for evaluation and further treatment of cluster seizures. The dog had behavioral abnormalities, and a prosencephalic lesion was suspected following neurological examination. The dog showed signs of learning difficulty. Magnetic resonance imaging of the brain revealed a remarkably smooth cerebral cortex with a reduced number of gyri, as well as a cystic lesion associated with the quadrigeminal cistern. A diagnosis of lissencephaly, concurrent with a quadrigeminal cisternal cyst, was made. High-dose and multiple anticonvulsants were necessary to control the seizures. This is the first report of lissencephaly in a Pekingese.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/28819088/