Peer-reviewed veterinary case report
Lissencephaly in a Pekingese.
- Journal:
- The Journal of veterinary medical science
- Year:
- 2017
- Authors:
- Shimbo, Genya et al.
- Affiliation:
- Obihiro University of Agriculture and Veterinary Medicine · Japan
- Species:
- dog
Abstract
A 1-year-old neutered male Pekingese was presented for evaluation and further treatment of cluster seizures. The dog had behavioral abnormalities, and a prosencephalic lesion was suspected following neurological examination. The dog showed signs of learning difficulty. Magnetic resonance imaging of the brain revealed a remarkably smooth cerebral cortex with a reduced number of gyri, as well as a cystic lesion associated with the quadrigeminal cistern. A diagnosis of lissencephaly, concurrent with a quadrigeminal cisternal cyst, was made. High-dose and multiple anticonvulsants were necessary to control the seizures. This is the first report of lissencephaly in a Pekingese.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/28819088/