Peer-reviewed veterinary case report
Seizures in an adult Australian Kelpie caused by lissencephaly
By Fraser, A R et al.·Published in Australian veterinary journal·2016·Faculty of Veterinary and Agricultural Sciences, Australia·View original on PubMed →
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Original publication title: Lissencephaly in an adult Australian Kelpie.
- Species:
- dog
Plain-English summary
A 6-year-old neutered male Australian Kelpie was brought in due to having seizures for the past two years. After a thorough examination and brain imaging, the vet diagnosed him with lissencephaly, a condition where the brain has fewer folds than normal. The dog was treated with anticonvulsants, and follow-up 11 months later showed that his seizures were well-controlled. This case suggests that dogs with lissencephaly can be managed effectively with medication.
People also search for: Australian Kelpie seizures treatment · dog lissencephaly symptoms · anticonvulsants for dogs
Abstract
CASE REPORT: A 6-year-old neutered male Australian Kelpie presented with a 2-year history of seizures. Neurological examination was consistent with a generalised prosencephalic lesion. Serum biochemical testing was performed in addition to magnetic resonance imaging of the brain and cerebrospinal fluid analysis. Magnetic resonance imaging revealed a reduction in the number of sulci and gyri in addition to cortical thickening, resulting in a diagnosis of lissencephaly. The dog was treated with anticonvulsants and follow-up information obtained from the referring veterinarian 11 months after diagnosis indicated that the dog had good seizure control. CONCLUSION: This is the first report of lissencephaly in the Australian Kelpie and would suggest that some dogs with the condition can be managed with long-term anticonvulsant medication.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/27021891/