Peer-reviewed veterinary case report
Brain blood flow patterns in dogs with epilepsy using SPECT imaging
By Huaijantug, Somkiat et al.·Published in The Journal of veterinary medical science·2020·Department of Companion Animals Clinical Sciences·View original on PubMed →
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Original publication title: Localization of cerebral hypoperfusion in dogs with refractory and non-refractory epilepsy using [99mTc] ethyl cysteinate dimer and single photon emission computed tomography.
- Species:
- dog
Plain-English summary
A group of dogs with epilepsy, some of whom had seizures that were difficult to control (refractory epilepsy), underwent brain scans to see if there were any areas with reduced blood flow. The scans showed that dogs with refractory epilepsy had more areas of reduced blood flow in the temporal lobe compared to those with non-refractory epilepsy. While the difference wasn't statistically significant, it suggests that issues in the temporal lobe might be linked to the more severe cases of epilepsy in dogs. Further research could help clarify this connection and improve treatment options.
People also search for: dog epilepsy treatment · why is my dog having seizures · refractory epilepsy in dogs · brain scan for dog seizures
Abstract
To evaluate the localization of functional deficit area in epileptogenic zones of the brain in seven refractory and seven non-refractory epilepsy dogs using technetium 99m labeled with ethyl cysteinate dimer and interictal single photon emission computed tomography [Tc-ECD SPECT] co-registration with Magnetic Resonance Imaging (MRI). Regions showing perfusion deficits in the SPECT images were analyzed by using the standard semiquantitative evaluation method to compare the level of cortical perfusion to the maximum number of counts within the cerebellum (max C), considered the area of reference. This study showed that SPECT imaging revealed abnormalities in several regions of the brain in both epilepsy groups. The refractory epilepsy dogs showed more frequency area of hypoperfusion in temporal lobe than non-refractory group with not statistically significance (P=0.28). The result suggests the lesion in temporal might be relevance with refractory epilepsy in canine patients.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/32188799/