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Peer-reviewed veterinary case report

Fluid-draining skin nodules from lymphangiosarcoma in young cat

By Jackson, Dorothy E et al.·Published in Journal of feline medicine and surgery·2011·Department of Veterinary Medicine and Surgery, United States·View original on PubMed

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Original publication title: Locally invasive lymphangiosarcoma in a young domestic shorthair.

Species:
cat
LymphomaBehaviour & energyCats

Plain-English summary

A 2-year-old female domestic shorthair cat was brought to the vet with fluid-filled pockets on her chest and under her front legs that had been draining for about 11 months. The skin in these areas was red, and the fluid was clear to slightly bloody. After examining skin samples, the vet found that the cat had a type of cancer called lymphangiosarcoma, which is a locally aggressive tumor affecting the lymphatic vessels. Treatment options were not detailed, but early diagnosis is crucial for managing this condition.

People also search for: cat skin lumps · domestic shorthair cancer symptoms · lymphangiosarcoma treatment for cats

Abstract

A 2-year-old, female spayed, domestic shorthair cat presented to the University of Missouri-Veterinary Medical Teaching Hospital (UMC-VMTH) with an approximately 11-month history of fluid-draining pockets along her ventral thorax and axillae. The skin in these regions was erythematous, and multiple areas drained a serous to serosanguinous fluid. Fluid-filled, nodules formed along the ventrum, but these nodules disappeared as fluid drained spontaneously. Histologic assessment of skin biopsies revealed areas of vascular proliferation extending along the deep margin of the section and rare instances of invasion into the superficial dermis. These vascular channels were devoid of cells, lined by variably pleomorphic endothelial cells which had a low mitotic index. Based on the mild to moderate pleomorphism, positive staining with prospero-related homeobox gene-1 (PROX-1), and the locally aggressive nature of the tumor, a final diagnosis of lymphangiosarcoma was made.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21880529/