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Peer-reviewed veterinary case report

Pekingese dog with brain inflammation lived 3 years on cyclosporine

By Jung, Dong-In et al.·Published in The Journal of veterinary medical science·2012·Research Institute of Life Sciences, South Korea·View original on PubMed

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Original publication title: Long-term immunosuppressive therapy with cyclosporine plus prednisolone for necrotizing meningoencephalitis in a Pekingese dog.

Species:
dog

Plain-English summary

A 4-year-old female Pekingese was brought to the vet because she was having trouble walking (ataxia) and experiencing seizures. After tests, the vet suspected she had a serious brain condition called necrotizing meningoencephalitis, which is inflammation of the brain and its protective layers. The dog was treated with a combination of cyclosporine and prednisolone, which are medications that suppress the immune system. Remarkably, she survived for nearly three years with this treatment, showing that it can be effective for managing this condition.

People also search for: Pekingese seizures treatment · dog ataxia causes · necrotizing meningoencephalitis in dogs treatment

Abstract

A 4-year-old intact female Pekingese dog was presented with ataxia and seizure episodes. Based on magnetic resonance imaging and cerebrospinal fluid analysis results, meningoencephalitis of unknown etiology was suspected. The present case survived for 1,096 days under cyclosporine plus prednisolone therapy and was definitively diagnosed with necrotizing meningoencephalitis. This report describes the clinical findings, serial magnetic resonance imaging characteristics and pathologic features of a necrotizing meningoencephalitis and long-term survival after cyclosporine with prednisolone therapy.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/22214856/