Peer-reviewed veterinary case report
Donkey with skin lupus treated long-term with methotrexate
By Mosca, Marion et al.·Published in Veterinary dermatology·2020·Université, France·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Long-term successful treatment of a donkey with cutaneous lupus erythematous with methotrexate.
- Species:
- horse
Plain-English summary
A 5-year-old neutered donkey was brought in for skin problems, including hair loss, redness, crusting, and scales. After testing, he was diagnosed with cutaneous lupus erythematosus, a rare skin condition caused by the immune system. The vet initially treated him with steroids and methotrexate, and for long-term management, methotrexate continued to be effective. The donkey showed significant improvement and maintained healthy skin over time with this treatment.
People also search for: donkey skin problems · cutaneous lupus erythematosus treatment · donkey hair loss causes · methotrexate for donkey skin condition
Abstract
Cutaneous lupus erythematosus (CLE) is a rare immune-mediated dermatitis. To the best of the authors' knowledge it has not been described in donkeys. A 5-year-old male neutered donkey, living in south-east France, was diagnosed with CLE. Clinical signs included generalized symmetrical areas of alopecia, erythema, crusting and scales. Diagnostic tests included examination of skin biopsy samples by histopathological and immunohistochemical analysis which demonstrated an interface dermatitis with CD8+ T cells. The skin condition was successfully treated initially with glucocorticoids and methotrexate; successful long-term maintenance was associated with administration of methotrexate.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/32293082/