Peer-reviewed veterinary case report
Dog with metastatic insulinoma lived over 2 years on prednisone
By Flesner, Brian K et al.·Published in Journal of the American Animal Hospital Association·2019·From the Department of Veterinary Medicine and Surgery, United States·View original on PubMed →
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Original publication title: Long-Term Survival and Glycemic Control with Toceranib Phosphate and Prednisone for a Metastatic Canine Insulinoma.
- Species:
- dog
Plain-English summary
A 9-year-old mixed-breed dog was diagnosed with a stage III pancreatic insulinoma, a type of cancer that affects insulin production and can lead to serious health issues. After surgery to remove part of the pancreas, the dog was treated with prednisone and toceranib phosphate, a medication often used for mast cell tumors. Remarkably, this combination helped maintain stable blood sugar levels and allowed the dog to live for over 24 months, which is much longer than the typical survival time for this condition.
People also search for: dog insulinoma treatment · canine cancer survival rates · prednisone for dog cancer
Abstract
Canine insulinoma is a highly metastatic neoplasm that is associated with a guarded to poor prognosis in dogs with distant metastases. A median survival of 6 mo has been reported for dogs with metastatic insulinoma. The dog in this report, diagnosed with stage III pancreatic insulinoma, had long-term glycemic control with survival of over 24 mo while receiving prednisone and toceranib phosphate after partial pancreatectomy. Toceranib phosphate has been shown to be an efficacious therapy for canine mast cell tumors with increasing evidence that it may be beneficial in the medical management of neuroendocrine tumors.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/30427714/