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Peer-reviewed veterinary case report

Long-term itraconazole treatment in dogs with Aspergillus terreus

By Kelly, S E et al.·Published in Australian veterinary journal·1995·School of Veterinary Studies, Australia·View original on PubMed

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Original publication title: Long-term survival of four dogs with disseminated Aspergillus terreus infection treated with itraconazole.

Species:
dog

Plain-English summary

Four dogs were diagnosed with a serious fungal infection called disseminated aspergillosis caused by Aspergillus terreus. They were treated with an antifungal medication called itraconazole for periods ranging from about six months to nearly three years. One dog fully recovered from the infection, while two others had to be euthanized after long treatment periods due to the disease's progression despite ongoing therapy. The fourth dog showed some improvement but was euthanized for unrelated reasons after about six months.

People also search for: dog fungal infection treatment · Aspergillus terreus in dogs · itraconazole for dogs aspergillosis

Abstract

Four dogs with disseminated aspergillosis caused by Aspergillus terreus were treated with oral itraconazole for 190 to 1095 days. Infection was eliminated in 1 dog. Two dogs were treated for 1000 and 1095 days but were eventually euthanased 572 and 485 days after treatment was stopped. At necropsy both dogs had widespread aspergillosis. The fourth dog was euthanased for other reasons after 190 days of treatment when it was showing a good clinical response although there was radiographic evidence that the disease was progressing.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/8579564/