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Peer-reviewed veterinary case report

Managing pemphigus foliaceus in a miniature donkey with oclacitinib

By Morales, Camilo J et al.·Published in Veterinary dermatology·2026·William R. Pritchard Veterinary Medical Teaching Hospital, United States·View original on PubMed

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Original publication title: Long-Term Use of Oclacitinib Maleate for the Management of Pemphigus Foliaceus in a Miniature Donkey.

Species:
horse

Plain-English summary

A 6-year-old miniature donkey was brought in for severe itching, scaling skin, crusty patches, and hair loss. The vet diagnosed her with pemphigus foliaceus, an autoimmune skin condition. For over four years, she was treated with oclacitinib maleate, a medication that helped manage her symptoms, sometimes combined with a low dose of prednisolone. Throughout this time, she showed no side effects or signs of toxicity, and her condition was successfully controlled.

People also search for: donkey skin problems · pemphigus foliaceus treatment · itching in miniature donkey · oclacitinib for skin issues in donkeys

Abstract

A 6-year-old miniature jenny was presented with pruritus, scaling, crusting and alopecia. Pemphigus foliaceus was diagnosed based on history, clinical presentation and histological findings. The jenny was successfully managed with oclacitinib maleate, with and without low-dose prednisolone, for over a 4 year period without adverse effects or signs of toxicity.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/41958441/