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Peer-reviewed veterinary case report

Rapidly growing tumor on dog's upper jaw diagnosed as low-grade

By Tsuchiya, T et al.·Published in Journal of comparative pathology·2012·Tokyo University of Agriculture and Technology, Japan·View original on PubMed

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Original publication title: Low-grade myofibroblastic sarcoma of the maxillary region in a dog.

Species:
dog

Plain-English summary

A 14-year-old mixed breed dog had a rapidly growing lump in the upper jaw that appeared over just two weeks. The tumor was found to be a low-grade myofibroblastic sarcoma, which is a type of cancer that arises from certain cells in the body. The dog's veterinarian likely performed a biopsy to confirm the diagnosis. Treatment options may include surgery to remove the tumor, and the prognosis can vary depending on how well the cancer responds to treatment.

People also search for: dog jaw tumor · mixed breed dog cancer treatment · lump on dog's face · myofibroblastic sarcoma in dogs

Abstract

A subcutaneous tumour was identified in the maxillary region of a 14-year-old mixed breed dog. This tumour had grown rapidly over 2 weeks. Microscopically, the tumour had ill-defined borders and was composed of bundles and whorls of atypical spindle cells accompanied by abundant collagen fibres. Immunohistochemically, neoplastic cells were immunoreactive for vimentin, α-smooth muscle actin and calponin and negative for S100 protein, von Willebrand factor, desmin and smoothelin. These results suggested that the neoplastic cells were derived from myofibroblasts and that the tumour was a low-grade myofibroblastic sarcoma.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21996034/