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Peer-reviewed veterinary case report

Lymphangiosarcoma causing lumps and swelling in 12 dogs

By Curran, K. M. et al.·Published in Veterinary and Comparative Oncology·2014·Flint Animal Cancer Center Colorado State University Fort Collins CO USA, United States·View original on Crossref

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Original publication title: Lymphangiosarcoma in 12 dogs: a case series (1998–2013)

Species:
dog

Plain-English summary

Twelve dogs with a rare type of cancer called lymphangiosarcoma (LAS) were treated over a 15-year period. Most of these dogs had noticeable masses or swelling on their neck, body, or limbs and had previously received wound care before their diagnosis. Treatment varied, with some dogs undergoing surgery, chemotherapy, or a combination of therapies. Dogs that received surgery tended to live longer, with some surviving over two years after treatment. One dog is still alive after surgery and chemotherapy, despite a recurrence of the cancer.

People also search for: dog cancer treatment options · lymphangiosarcoma in dogs · dog swelling treatment · dog surgery for cancer · dog chemotherapy side effects

Abstract

AbstractLymphangiosarcoma (LAS) is an uncommon malignant neoplasia arising from lymphatic endothelium; little information exists regarding therapy. Single institutional retrospective review for canineLAShistopathology diagnoses over a 15‐year period yielded 12 dogs. Ten dogs were presented for a mass and/or swelling at cervical, trunk or limb regions. Prior to diagnosis, 10 dogs received empiric wound therapy. Cytology performed in 10 consisted of mild inflammation. Survival ranged from 60, 168 and 876 days for three dogs with palliation; 90 days with prednisone in one; 182 days with chemotherapy in one; 240, 267, 487, 630 and 941 days for five receiving surgery; and 574 days for one receiving surgery, radiation and chemotherapy. One dog is alive with recurrence at 243 days following surgery and carboplatin chemotherapy. Clinical improvement existed inLASdogs receiving multimodal therapies. Early tissue biopsies are recommended for progressive oedematous lesions of unknown origin.

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Original publication on Crossref: https://doi.org/10.1111/vco.12087