Peer-reviewed veterinary case report
Lymphangiosarcoma causing lumps and swelling in 12 dogs and their
By Curran, K M et al.·Published in Veterinary and comparative oncology·2016·Colorado State University, United States·View original on PubMed →
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Original publication title: Lymphangiosarcoma in 12 dogs: a case series (1998-2013).
- Species:
- dog
Plain-English summary
Twelve dogs with a rare type of cancer called lymphangiosarcoma (LAS) were treated at a veterinary clinic over 15 years. Most of these dogs showed signs like swelling or masses on their neck, body, or legs. Before being diagnosed, many received treatment for wounds, but that didn't help. Some dogs had surgery, while others received chemotherapy or radiation, leading to varying survival times. The best outcomes were seen in dogs that had surgery combined with other treatments, with one dog living over two years after treatment. Early biopsies are suggested for any unexplained swelling to catch this cancer sooner.
People also search for: dog swelling neck · lymphangiosarcoma treatment in dogs · dog cancer survival rates · dog surgery for tumors · lymphangiosarcoma prognosis
Abstract
Lymphangiosarcoma (LAS) is an uncommon malignant neoplasia arising from lymphatic endothelium; little information exists regarding therapy. Single institutional retrospective review for canine LAS histopathology diagnoses over a 15-year period yielded 12 dogs. Ten dogs were presented for a mass and/or swelling at cervical, trunk or limb regions. Prior to diagnosis, 10 dogs received empiric wound therapy. Cytology performed in 10 consisted of mild inflammation. Survival ranged from 60, 168 and 876 days for three dogs with palliation; 90 days with prednisone in one; 182 days with chemotherapy in one; 240, 267, 487, 630 and 941 days for five receiving surgery; and 574 days for one receiving surgery, radiation and chemotherapy. One dog is alive with recurrence at 243 days following surgery and carboplatin chemotherapy. Clinical improvement existed in LAS dogs receiving multimodal therapies. Early tissue biopsies are recommended for progressive oedematous lesions of unknown origin.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24612140/