Peer-reviewed veterinary case report
Dog with ear tumor causing bone growth in the ear flap
By Mineshige, Takayuki et al.·Published in The Journal of veterinary medical science·2015·School of Veterinary Medicine, Japan·View original on PubMed →
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Original publication title: Lymphangiosarcoma with bone formation of the auricle in a dog.
- Species:
- dog
Plain-English summary
A 12-year-old mixed-breed female dog was brought to the vet because of tumors on her left ear. After testing, the tumors were diagnosed as lymphangiosarcoma, a type of cancer that affects the lymphatic system. Interestingly, the tumor also showed signs of bone formation, which is unusual. The vet will likely discuss treatment options such as surgery or chemotherapy to manage the cancer and improve the dog's quality of life.
People also search for: dog ear tumor treatment · lymphangiosarcoma in dogs · signs of cancer in dogs
Abstract
A 12-year-old mixed-breed neutered female dog was referred with cutaneous tumors at the left auricle. Histologically, the cutaneous tumor located in the dermis comprised numerous clefts and cavernous channels lined by neoplastic endothelial cells with no erythrocytes. Bone tissue without direct contact with neoplastic cells was seen in the well-developed stromal connective tissue. The neoplastic endothelial cells exhibited mild to moderate atypia. Immunohistochemically, neoplastic cells were positive for vimentin and negative for cytokeratin and factor VIII-related antigen. Basement membrane around the neoplastic lumens was positive for laminin in a linear or granular pattern. Ultrastructural examination revealed discontinuous basement membrane beneath the tumor cells. Histopathological features of this case were consistent with lymphangiosarcoma, and stromal ossification was characteristic.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/25716121/