Peer-reviewed veterinary case report
Lymphoepithelial thymoma tumor in 14-year-old Samoyed dog
By Akiyama, Tomomi et al.·Published in The Journal of veterinary medical science·2009·Department of Veterinary Pathology, Japan·View original on PubMed →
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Original publication title: Lymphoepithelial thymoma characterized by proliferation of spindle cells in a Samoyed dog.
- Species:
- dog
Plain-English summary
A 14-year-old Samoyed was diagnosed with a lymphoepithelial thymoma, a type of tumor in the chest, after showing symptoms of myasthenia gravis (a condition that causes muscle weakness) since he was 6 months old. During the examination after his passing, a dark red mass with nodules was found in his chest area. The tumor was made up of abnormal cells and some immune cells, which were identified through special tests. Unfortunately, this condition is serious, and the dog did not recover.
People also search for: Samoyed dog tumor symptoms · myasthenia gravis in dogs · thymoma treatment for dogs
Abstract
Lymphoepithelial thymoma was diagnosed in a 14-year-old Samoyed dog with clinical symptoms of myasthenia gravis at 6 months of age. At necropsy, dark red-colored mass with many nodular protuberances was found in the anterior mediastinal area. Histologically, the mass consisted of solid proliferation of neoplastic cells with spindle nuclei and cytoplasm and a few lymphocytes, which is separated by an abundant fibrous and adipose tissue. Immunohistochemically, spindle cells were positive for cytokeratin, and infiltrating lymphocytes were positive for CD3. On the basis of these findings, this tumor was diagnosed as lymphoepithelial thymoma, which is morphologically similar to type A thymoma in humans.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19801913/