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Peer-reviewed veterinary case report

Lymphosarcoma and associated immune-mediated hemolytic anemia and thrombocytopenia in horses.

Journal:
Journal of the American Veterinary Medical Association
Year:
1984
Authors:
Reef, V B et al.
Species:
horse

Abstract

Three horses with equine lymphosarcoma were examined because of clinical signs including chronic weight loss, respiratory distress, peripheral edema, and chronic colic. Clinicopathologic findings included evidence of an immune-mediated hemolytic anemia. Immune-mediated thrombocytopenia also was diagnosed in 1 of the horses and suspected in another. One horse died in spite of treatment, 1 died 5 hours after surgical removal of a tumor encircling the jejunum, and 1 was euthanatized because of deteriorating condition. Necropsy of each horse revealed extensive neoplastic infiltration of peripheral lymph nodes and abdominal or thoracic viscera with neoplastic lymphocytes.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/6546561/