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Peer-reviewed veterinary case report

MRI shows malignant melanoma in a Beagle's eye

By Kato, Kumiko et al.·Published in The Journal of veterinary medical science·2005·Graduate School of Agricultural and Life Sciences, Japan·View original on PubMed

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Original publication title: Magnetic resonance imaging of a canine eye with melanoma.

Species:
dog

Plain-English summary

An 8-year-old Beagle was brought in because its left eye was bulging out for the past two months. The vet couldn't see inside the eye due to cloudiness, and an ultrasound showed the eye was misshapen and out of place. Magnetic resonance imaging (MRI) revealed a tumor that looked similar to melanoma found in humans. The tumor was confirmed to be malignant intraocular melanoma. While this is just one case, it suggests that dogs with eye tumors may show similar MRI characteristics as humans.

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Abstract

An 8-year-old Beagle dog had exophthalmos of the left eye for the last two past months. On ophthalmoscopy, the intraocular lesion could not be evaluated due to the opacity of the cornea. Ultrasonography revealed that the eyeball was distorted in shape and shifted in position, however, the precise lesion could not be identified. On magnetic resonance (MR) imaging, the lesion was observed as hyperintense on T1-weighted and hypointense on T2-weighted images, similar to those reported in human melanoma. The lesion was histologically diagnosed to be malignant intraocular melanoma. Though this is only a case report, canine ocular melanoma may show the similar characteristic MR images as in human uveal malignant melanoma.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15750314/