Peer-reviewed veterinary case report
Dog with malignant jaw tumor spreading to lungs and liver
By Ueki, H et al.·Published in Veterinary pathology·2004·Department of Veterinary Pathology, Japan·View original on PubMed →
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Original publication title: Malignant ameloblastic fibro-odontoma in a dog.
- Species:
- dog
Plain-English summary
An 11-year-old male Collie was brought in with swelling on his face caused by tumor masses in his gums. Unfortunately, after he passed away, a postmortem exam showed that the tumor had spread to his lymph nodes, lungs, liver, and eye area. The tumor was identified as a malignant ameloblastic fibro-odontoma, which is a type of cancer that affects the mouth. This case is significant as it is the first known instance of this type of tumor spreading to other organs in a dog.
People also search for: dog face swelling tumor · Collie mouth cancer symptoms · malignant ameloblastic fibro-odontoma in dogs
Abstract
An 11-year-old male Collie was presented with a swelling of the face caused by tumor masses arising from the gingiva. Postmortem examination revealed metastases to the lymph nodes, lung, liver, and orbital cavity. Histologically, the tumor represented a combination of fibrosarcomatous proliferation, pulpal mesenchyme, and undifferentiated odontogenic epithelium, with a follicular or plexiform growth pattern. In addition, the follicular areas of the tumor showed a biphasic character, and there were numerous apoptotic cells in plexiform areas. Furthermore, acidophilic material resembling dysplastic dentine or enamel matrix was observed in the metastatic lesion in the lung. Based on the histological characters, the present case was diagnosed as malignant ameloblastic fibro-odontoma. This study is the first known description of a possible malignant ameloblastic fibro-odontoma in a dog with metastasis to distant organs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15017034/