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Peer-reviewed veterinary case report

Malignant oral tumor in an 8-year-old cat's mouth

By Boonsriroj, Hassadin et al.·Published in The Journal of veterinary medical science·2014·Department of Veterinary Pathology, Japan·View original on PubMed

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Original publication title: Malignant epithelioid schwannoma of the oral cavity in a cat.

Species:
cat

Plain-English summary

An 8-year-old domestic short-hair cat was found to have a malignant tumor in its mouth, specifically in the gums near the upper left premolars and molars. The tumor was made up of abnormal cells and showed a unique growth pattern. This type of tumor, called a malignant epithelioid schwannoma, is rare in cats. Unfortunately, the abstract does not provide information on treatment or the outcome for this cat.

People also search for: cat mouth tumor · feline oral cancer symptoms · treatment for cat gingival mass

Abstract

A malignant epithelioid schwannoma of the oral cavity was diagnosed in an 8-year-old domestic short-hair cat. The mass was located in the gingiva of the upper left premolar to molar region and showed multinodular growth patterns. The mass comprised epithelioid cells arranged in densely packed sheets. Tumor cells had large, round to oval nuclei with prominent nucleoli and an abundant eosinophilic cytoplasm. Immunohistochemically, most of the tumor cells were positive for S-100 protein, glial fibrillary acidic protein and vimentin, but all lacked melanoma-associated antigen and muscle and neuroendocrine markers. Stains for type IV collagen showed linear immunoreactivity around single cells and groups of cells. Ultrastructurally, tumor cells were separated by a well-defined basement membrane, and interdigitating cell processes were observed. To our knowledge, this is the first report of feline malignant epithelioid schwannoma.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24632862/