Peer-reviewed veterinary case report
T-cell lymphoma in nasal cavity and sinuses of dog
By Kaldrymidou, E et al.·Published in Journal of veterinary medicine. A, Physiology, pathology, clinical medicine·2000·Faculty of Veterinary Medicine·View original on PubMed →
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Original publication title: Malignant lymphoma in nasal cavity and paranasal sinuses of a dog.
- Species:
- dog
Plain-English summary
A crossbred German Shepherd was diagnosed with a serious type of cancer called T-cell lymphoma, which was located in the nasal cavity and sinuses. The tumor was found to be highly malignant, meaning it was aggressive and could spread quickly. Tests showed that the cancer cells had specific markers, confirming the diagnosis. Unfortunately, the details of treatment and outcome were not provided, but it's important for pet owners to discuss any signs of nasal issues, such as difficulty breathing or nasal discharge, with their veterinarian.
People also search for: dog nasal cancer symptoms · German Shepherd lymphoma treatment · dog breathing problems cancer
Abstract
A case of a canine large cell type T-cell lymphoma, with features of high-grade malignancy is described. The tumour was found confined in the nasal cavity and the paranasal sinuses of a crossbred German Shepherd dog. Histological examination revealed the features of a highly malignant large cell lymphoma. Ultrastructurally, the lymphoid tumour cells bore cytoplasmic protrusions that interdigitated tightly. From a panel of tumour markers used, the neoplastic cells were stained only for vimentin. Immunophenotyping of the tumour cells by means of CD3, CD79, kappa-light chains and lambda-light chains detection was undertaken. The tumour stained only for CD3 and was classified as T-cell lymphoma.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/11075536/