Peer-reviewed veterinary case report
Rare malignant eye tumor called teratoid medulloepithelioma
By Salih, Amna et al.·Published in Journal of comparative pathology·2023·Ophthalmology Department, United Kingdom·View original on PubMed →
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Original publication title: Malignant ocular teratoid medulloepithelioma in two cats.
- Species:
- cat
Plain-English summary
Two cats were brought to the vet with rapidly growing eye tumors that were causing serious problems. After a thorough eye exam, the vets found tumors in the eyes that were affecting the surrounding structures. Both cats underwent surgery to remove the affected eyes (enucleation), and lab tests confirmed the presence of a rare type of tumor called teratoid medulloepithelioma. Fortunately, after several years of follow-up, neither cat showed signs of the cancer returning or spreading, suggesting that the surgery was successful in treating the condition.
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Abstract
Medulloepithelioma is a type of rare primitive neuroectodermal tumour. Most medulloepitheliomas are intraocular and they have been most frequently reported in horses and dogs. A single feline case has been reported but the teratoid form has not been previously reported in cats. Two cats presented with rapidly expanding intraocular masses and ophthalmic examination revealed vascularized uveal tumours extending into the anterior chamber and vitreous chamber. Following enucleation, histopathological examination of each case revealed a focally extensive infiltrative neoplasm that replaced the uveal tract, with retinal detachment and scleral vascular invasion. Rosettes, medullary tubes and heterotopic tissue were present. During follow-up periods of 3.4 and 8.8 years, no evidence of orbital recurrence or metastasis was found in either cat. To the best of our knowledge, these are the first case reports of teratoid medulloepithelioma in cats. Although the risk of metastasis cannot be excluded, as in other species, these findings support enucleation as a curative intervention.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/36646033/