Peer-reviewed veterinary case report
Cat with malignant estrogen-producing ovarian tumor causing abdominal
By Machida, Y et al.·Published in Journal of comparative pathology·2017·Faculty of Veterinary Medicine, Japan·View original on PubMed →
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Original publication title: Malignant Oestrogen-producing Teratoma in a Cat.
- Species:
- cat
Plain-English summary
A 5-year-old female domestic shorthair cat was brought to the vet with a swollen belly. Blood tests showed she had very high levels of estrogen, a hormone. During surgery, the vet found a large cystic mass in her right ovary that was producing this hormone. The mass was identified as a rare and malignant tumor that contained various types of tissue. Unfortunately, due to the nature of the tumor, the prognosis may not be good, and further treatment options would need to be discussed with the veterinarian.
People also search for: cat swollen belly · high estrogen in cats · ovarian tumor in cats · cat abdominal distension treatment
Abstract
A 5-year-old female domestic shorthair cat was presented with abdominal distension and serum biochemical evaluation indicated a high concentration of oestradiol (32.81 pg/ml). Exploratory laparotomy revealed a large cystic mass in the right ovary with cystic fluid containing a high level of oestradiol (18.80 pg/ml). The tumour was composed of immature neuroectodermal tissue, mature cartilage, smooth muscle, adipose tissue and aggregated, poorly differentiated mesenchymal cells. It contained cysts of various sizes that were lined by epithelium of different types. The basal layer of the lining epithelium was shown to express aromatase by immunohistochemistry. The findings suggest that this was a novel, malignant, oestrogen-secreting teratoma and that the aromatase-positive, neoplastic cells may have been the source of elevated levels of serum oestrogen.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/28017339/