Peer-reviewed veterinary case report
Malignant nerve sheath tumor with lung and lymph node spread in cat
By Buza, Elizabeth L et al.·Published in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·2012·Department of Pathobiology, United States·View original on PubMed →
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Original publication title: Malignant peripheral nerve sheath tumor in a cat with nodal and pulmonary metastases.
- Species:
- cat
Plain-English summary
A 11-year-old Domestic Shorthair cat was found to have a malignant tumor that started in the mouth and spread to the lymph nodes and lungs. Initially, the tumor was thought to be benign, but further examination revealed it was aggressive and had metastasized. Unfortunately, the cat's condition was serious, and the cancer was confirmed at necropsy. This case highlights the importance of monitoring unusual growths in pets, as they can sometimes turn out to be more serious than initially believed.
People also search for: cat mouth tumor · cat cancer symptoms · cat lung metastasis treatment
Abstract
Peripheral nerve sheath tumors in domestic cats are infrequently reported and are often locally invasive. An 11-year-old Domestic Shorthair cat was originally diagnosed with a right maxillary benign peripheral nerve sheath tumor at incisional biopsy. At necropsy, the neoplasm had features of malignancy including metastases to the regional lymph nodes and lung. Histologically, the neoplasm contained 2 distinct regions: spindle cells arranged in dense interwoven bundles with Antoni A areas and Verocay bodies and Antoni B regions with loosely arranged spindle cells separated by a mucinous matrix. Immunohistochemically, the neoplastic cells in the primary mass and right mandibular lymph node were strongly positive for vimentin, S-100, and glial fibrillar acidic protein. The neoplastic cells within the lung were strongly positive for vimentin and weakly positive for S-100 and glial fibrillar acidic protein.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/22604770/