Peer-reviewed veterinary case report
Malignant pilomatricoma skin tumors in 3 dogs with metastasis
By Carroll, E E et al.·Published in Veterinary pathology·2010·Armed Forces Institute of Pathology, United States·View original on PubMed →
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Original publication title: Malignant pilomatricoma in 3 dogs.
- Species:
- dog
Plain-English summary
A 12-year-old Giant Schnauzer, an 8-year-old Airedale Terrier, and a 7-year-old Bassett Hound were diagnosed with malignant pilomatricoma, a rare type of skin tumor. In two of the dogs, the cancer had spread to other parts of the body, including the bones. The tumors showed specific features under the microscope that confirmed their malignant nature. This suggests that malignant pilomatricoma might be more common in dogs than previously thought. Treatment options were not detailed, but early detection and intervention are crucial for managing this serious condition.
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Abstract
Malignant pilomatricoma, also known as pilomatrix carcinoma and calcifying epitheliocarcinoma (in the human literature), has been considered a rare neoplasm of dogs. The authors present 3 canine cases of malignant pilomatricoma (2 with distant metastasis) and compare its behavior with reported behavior. Cases include an 8-year-old spayed female Airedale Terrier, a 7-year-old male Bassett Hound, and a 12-year-old intact male Giant Schnauzer. In all cases, the histologic features included trabeculae of basaloid cells, abrupt keratinization, "ghost" or "shadow" cells, and various features of malignancy consistent with a diagnosis of malignant pilomatricoma. Metastasis, including that to bone, was confirmed in 2 cases. Four cases of the 13 canine pilomatricomas diagnosed within a 24-month period (2006-2008) at the Ohio State University (2 of which are discussed in this report) were classified as malignant, which suggests that malignant pilomatricoma is more common than previously reported.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20466858/