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Peer-reviewed veterinary case report

Cat with stomach tumor treated successfully with toceranib phosphate

By McGregor, O et al.·Published in Australian veterinary journal·2020·Northside Veterinary Specialists, United Kingdom·View original on PubMed

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Original publication title: Management of a feline gastric stromal cell tumour with toceranib phosphate: a case study.

Species:
cat

Plain-English summary

A 15-year-old female domestic longhaired cat was brought in for a routine vaccination when the vet found an abdominal mass. The owner mentioned that the cat had been vomiting occasionally, but there were no other signs of illness. An ultrasound confirmed a gastric tumor, which was identified as a gastrointestinal stromal cell tumor (GIST). The cat was treated with toceranib phosphate, and after 18 months, the tumor remained stable, and the cat was still alive and doing well.

People also search for: cat vomiting · cat abdominal mass · feline gastric tumor treatment · toceranib for cats · GIST in cats

Abstract

BACKGROUND: A fifteen-year old, female spayed domestic longhaired cat was presented for a routine vaccination during which an incidental abdominal mass was palpated. After further inquiry, occasional vomiting was reported to occur once every few weeks to months, associated with no other gastrointestinal signs. CASE REPORT: Ultrasonography revealed a gastric mass. Histopathology and immunohistochemistry confirmed a CD117 positive, smooth muscle actin and desmin negative neoplasm, consistent with a gastrointestinal stromal cell tumour (GIST). Treatment was initiated with toceranib phosphate resulting in stable disease for over eighteen months, and the patient was still alive at the time of writing. CONCLUSION: GISTs are rare in cats and this is the first report of medical management of feline GIST using toceranib.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/31971262/