Peer-reviewed veterinary case report
Cat with destructive jaw tumor called mandibular odontogenic sarcoma
By Ramírez, Gustavo A et al.·Published in Acta veterinaria Hungarica·2017·HISTOVET Veterinary Diagnostic Service, Spain·View original on PubMed →
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Original publication title: Mandibular odontogenic sarcoma (ameloblastic fibrodentinosarcoma) in an aged cat - Short communication.
- Species:
- cat
Plain-English summary
A 13-year-old male cat was brought to the vet with a strange mass in his jaw that was causing bone loss. The mass was found to have both benign and malignant cells, indicating a rare type of tumor called ameloblastic fibrodentinosarcoma, which has not been previously reported in cats. The vet used special tests to confirm the diagnosis, and while the tumor was concerning, the findings helped understand its nature. Treatment options would depend on the extent of the tumor and the cat's overall health, but early detection is key for better outcomes.
People also search for: cat jaw tumor · cat oral mass treatment · what is ameloblastic fibrodentinosarcoma in cats
Abstract
A 13-year-old male cat presented with an ill-defined mass in the rostral mandible causing destruction and loss of alveolar bone. Microscopically, the mass consisted of cords or islands of benign odontogenic epithelium and a malignant, pleomorphic spindle-shaped cell component with dysplastic dentine formation. Immunohistochemically, neoplastic mesenchymal cells proved to be strongly positive for vimentin and negative for cytokeratins, desmin, actin and S100 protein; the Ki67 proliferation index was high. Morphological and immunohistochemical features largely overlap those reported for ameloblastic fibrodentinosarcoma, an uncommon histologic subtype of odontogenic sarcoma recognised in humans but no reported previously in animals. Ki-67 expression assessment may help to discriminate between malignant and benign forms of odontogenic tumours but the final diagnosis is mainly morphological.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/28244329/