Peer-reviewed veterinary case report
Dog jaw tumor treated with frozen bone graft reconstruction
By Okamura, Yasuhiko et al.·Published in Journal of the American Animal Hospital Association·2017·From the Cooperative Department of Veterinary Medicine, Japan·View original on PubMed →
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Original publication title: Mandibular Reconstruction by Using a Liquid Nitrogen-Treated Autograft in a Dog with an Oral Tumor.
- Species:
- dog
Plain-English summary
A 10-year-old female German Shepherd was brought in with a large tumor on her lower jaw, which turned out to be a combination of a benign growth and a malignant melanoma. The vet removed the tumor and part of her jaw, then treated the removed bone by freezing it with liquid nitrogen before putting it back in place. This innovative approach allowed new bone to grow in the gap, and the dog was able to eat normally afterward. Unfortunately, the malignant melanoma came back about five months later, leading to another surgery to remove more of her jaw.
People also search for: dog jaw tumor treatment · German Shepherd oral tumor surgery · malignant melanoma in dogs
Abstract
A 10 yr old intact female German shepherd dog presented with a large peripheral odontogenic fibroma and malignant melanoma on her lower jaw. The tumor was resected with a unilateral subtotal rostral hemimandibulectomy. After the mandible was removed, it was devitalized intraoperatively by freezing it in liquid nitrogen. It was subsequently reimplanted. New bone tissue formed in the gap between the frozen bone and the host bone. The regenerated bone contained osteocytes, osteoblasts, and blood vessels. The cosmetic appearance of the dog was preserved. The dog had normal mastication. The malignant melanoma recurred rostral of the left canine tooth at 159 days after the reconstruction surgery. A subtotal hemimandibulectomy was consequently performed. This is the first reported case of mandibular reconstruction using a liquid nitrogen-treated autograft in a dog with oral tumors.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/28291396/