Peer-reviewed veterinary case report
Dog with recurring jaw bone cancer treated with surgery
By Moe, L et al.·Published in The Journal of small animal practice·1996·Department of Small Animal Clinical Sciences·View original on PubMed →
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Original publication title: Maxillectomy and targeted radionuclide therapy with 153Sm-EDTMP in a recurrent canine osteosarcoma.
- Species:
- dog
Plain-English summary
An eight-year-old dog with a recurring bone cancer called osteosarcoma underwent surgery to remove part of its upper jaw and received a special radiation treatment. This treatment involved two injections of a bone-targeting radioactive substance, given 15 weeks apart. After the treatments, the dog experienced a temporary drop in some blood cell counts but recovered well. At a follow-up appointment 21 months later, there were no signs of cancer returning, and the dog was in excellent health with only minor issues from the surgery. This combination of surgery and radiation therapy appears to be a promising option for treating this type of cancer in dogs.
People also search for: dog osteosarcoma treatment · canine jaw surgery recovery · radiation therapy for dog cancer
Abstract
An eight-year-old dog with a local relapse of an osteosarcoma was treated with partial maxillectomy and systemic radionuclide therapy that involved two injections, 43 and 45 megabecquerels per kg bodyweight of the bone-seeking agent samarium-153-ethylenediaminetetramethylene phosphonic acid (153Sm-EDTMP), 15 weeks apart. A transient drop in white blood cell count and platelet count was observed following each 153Sm-EDTMP treatment. Follow-up 21 months after surgery revealed no evidence of local recurrence or metastases. The dog was in excellent condition, suffering only minor sequelae from the surgical procedure. Compared with historical controls treated with surgery alone, the combination of surgery and systemic radionuclide therapy seems a promising strategy for the treatment of canine osteosarcoma.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/8736231/