Peer-reviewed veterinary case report
Mediastinal lymphoma with complete atrioventricular block in a horse.
- Journal:
- The Journal of veterinary medical science
- Year:
- 2008
- Authors:
- Sugiyama, Akihiko et al.
- Affiliation:
- Department of Veterinary Laboratory Medicine · Japan
- Species:
- horse
Plain-English summary
A 15-year-old neutered male pony was brought in because he had been losing weight for the past four months. During the examination, the vet found that his heart was beating very slowly and he had a complete block in the electrical signals that control heartbeats. After the pony passed away, a thorough examination revealed a large tumor in the chest area and swollen lymph nodes in the neck. The tumor was made up of abnormal lymphoid cells, which are a type of immune cell. This case is notable because it is the first time such a tumor has been linked to heart block in horses. Unfortunately, the treatment options for this condition were not mentioned, but the outcome was not favorable.
Abstract
A 15-year-old, neutered-male pony presented with a history of weight loss during 4 months. Clinical evaluation revealed severe bradycardia and complete atrioventricular block. At necropsy, a lobulated mass in the anterior mediastinum and moderate enlargement of the superficial cervical lymph nodes were observed. The vagus nerve and the brachiocephalic trunk were embedded in this anterior mediastinal tumor. Histologically, the mass was composed of sheets of neoplastic lymphoid cells expressing CD3, with a low mitotic rate. To the best of our knowledge, this is the first reported case of mediastinal lymphoma associated with complete atrioventricular block in horses.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/18981668/