Peer-reviewed veterinary case report
Cat developed jaw bone death after long bisphosphonate use
By Larson, Melinda J et al.·Published in Journal of veterinary internal medicine·2019·BluePearl Veterinary Partners, United States·View original on PubMed →
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Original publication title: Medication-related osteonecrosis of the jaw after long-term bisphosphonate treatment in a cat.
- Species:
- cat
Plain-English summary
A 12-year-old female domestic medium hair cat was brought in for a nonhealing sore in her mouth. She had been treated with a medication called bisphosphonate for over three years due to high calcium levels in her blood. The vet found exposed bone in her mouth, which was linked to the long-term use of the medication. After a combination of medical and surgical treatments, her mouth healed completely after six months.
People also search for: cat mouth sore treatment · bisphosphonate side effects in cats · cat oral ulcer healing time
Abstract
A 12-year-old, neutered female, domestic medium hair cat was evaluated for a nonhealing, oral mucosal ulceration. The cat had a history of idiopathic hypercalcemia that had been treated with a bisphosphonate for 41 months. Oral examination identified exposed maxillary bone adjacent to a previous extraction site. Histopathology of the exposed bone and associated mucosa was most consistent with medication-related osteonecrosis of the jaw. Treatment involved both medical and surgical interventions. Oral mucosal healing occurred after 6 months of treatment.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/30663796/