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Peer-reviewed veterinary case report

Brain bone cancer (meningeal osteosarcoma) in a dog

By P. R. R. Moreira et al.·Published in Veterinária Notícias·2021·View original on Semantic Scholar

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Original publication title: Meningeal osteosarcoma in a dog’s brain

Species:
dog

Plain-English summary

A male mixed-breed dog was brought to the vet because he was overly excited, had decreased reflexes, and was experiencing seizures. Unfortunately, despite efforts to help him, his condition worsened, and he was euthanized. A necropsy revealed that he had a rare type of bone cancer called meningeal osteosarcoma, which started in the protective membranes of the brain. This case highlights how unusual this type of cancer is in dogs, as it typically arises in bones rather than soft tissues like the meninges.

People also search for: dog seizures causes · mixed breed dog cancer symptoms · why is my dog overly excited · treatment for dog brain tumors · dog euthanasia decision

Abstract

Osteosarcoma is the most common bone cancer in dogs. It has a high invasion capacity, commonly metastasize and it mainly arises in the medullary canal of long bones of the appendicular and axial skeleton, rarely affecting primarily extra-skeletal sites. Osteosarcoma of primary meningeal origin is extremely rare in human and veterinary medicine. A male, mixed breed dog was admitted at the Veterinary Hospital with a history of being overly excited, having decreased neurological reflexes and development of seizures. As the situation evolved, the animal was euthanized. The animal was referred to the Veterinary Pathology Service for necroscopic examination. The objective of this report was to describe a case of primary extra-skeletal osteosarcoma of the meninges in a dog, which presented clinical signs compatible with a disease originating in the central nervous system and which was diagnosed by histopathological and immunohistochemical analysis.

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Original publication on Semantic Scholar: https://www.semanticscholar.org/paper/9a5d4d429357c5d1ac394c00ad178b7aa34f37fe