Peer-reviewed veterinary case report
Meningioma tumor and stroke in three dogs with seizures
By Frank, Lisa et al.·Published in BMC veterinary research·2020·Department of Small Animal Medicine and Surgery, Germany·View original on PubMed →
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Original publication title: Meningioma and associated cerebral infarction in three dogs.
- Species:
- dog
Plain-English summary
Three dogs experienced sudden seizures and neurological problems due to meningiomas, which are tumors in the brain. They had chronic seizures but then quickly worsened, showing signs like weakness and confusion. MRI scans showed tumors and areas of brain damage caused by reduced blood flow. In two dogs, a necropsy confirmed the presence of meningiomas and brain damage, while the third dog improved with symptomatic treatment, allowing it to have a better quality of life.
People also search for: dog seizures sudden onset · meningioma treatment in dogs · dog brain tumor symptoms
Abstract
BACKGROUND: In dogs, meningiomas mostly cause chronic progressive clinical signs due to slow tumor growth. CASE PRESENTATION: In contrast, three dogs were presented with the history of chronic generalized tonic-clonic seizures and peracute deterioration with sudden onset of neurological deficits in accordance with an extensive unilateral forebrain lesion. Magnetic resonance imaging examinations of the dogs revealed a well-delineated extraaxial T2W hyperintense mass in the rostral forebrain with homogeneous contrast enhancement. Additionally, an intraaxial, well-demarcated, unilateral lesion was apparent in the parenchyma supplied by the middle cerebral artery. In two cases, necropsy revealed meningothelial meningioma in the rostral fossa and marked eosinophilic neuronal necrosis, a sign of ischemia, focal malacia, edema and gliosis in the temporal lobe and hippocampus because of a focal thrombosis of the middle cerebral artery. In the third case symptomatic treatment resulted in improvement of clinical signs enabling a good quality of life for the patient. CONCLUSIONS: In dogs with structural epilepsy caused by meningioma, acute deterioration of clinical signs can be associated with ischemic infarctions as a potential complication.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/32503537/