Peer-reviewed veterinary case report
Dog with brain tumor causing vision loss and seizures that spread
By Siudak, K et al.·Published in Veterinary pathology·2015·Institut fü, Germany·View original on PubMed →
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Original publication title: Metastasizing Esthesioneuroblastoma in a Dog.
- Species:
- dog
Plain-English summary
A 7-year-old Afghan hound was brought in for disorientation, loss of vision, and seizures. An MRI revealed a large tumor affecting the dog's nasal area, which was pressing on nearby structures. The vet successfully removed about 80% of the tumor, but it came back a few months later. Unfortunately, the dog developed severe breathing problems and was found to have a liver tumor, leading to the difficult decision to euthanize. The tumors were diagnosed as metastasizing esthesioneuroblastoma, indicating that the cancer had spread to other parts of the body.
People also search for: dog seizures and disorientation · Afghan hound nasal tumor · dog breathing problems liver tumor
Abstract
A 7-year-old Afghan hound presented with a history of disorientation, loss of vision, and seizures. Magnetic resonance imaging helped identify a mass at the level of the main olfactory bulb that compressed and displaced adjacent tissues in the cribriform plate into the nasal cavity and nasopharynx. Bony structures were osteolytic. After removing almost 80% of the mass, the tumor recurred a few months later. Due to severe respiratory distress and subsequent to an ultrasound diagnosis of a liver tumor, the dog was euthanized. In addition to the nasal mass, a single nodule in the liver and multiple nodules in the lung were present. All masses had similar cell morphology and were diagnosed as metastasizing esthesioneuroblastoma. The neoplastic cells expressed neuron-specific enolase and chromogranin A, and a few cells within the nasal mass were positive for cytokeratin. This is the first description of a canine esthesioneuroblastoma with distant metastases.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/25428407/