Peer-reviewed veterinary case report
Dog with methaemoglobinaemia after hydroxyurea poisoning
By Wray, J D·Published in The Journal of small animal practice·2008·Centre for Small Animal Studies·View original on PubMed →
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Original publication title: Methaemoglobinaemia caused by hydroxycarbamide (hydroxyurea) ingestion in a dog.
- Species:
- dog
Plain-English summary
A 3-year-old female neutered greyhound was brought to the vet after eating her owner's hydroxycarbamide (hydroxyurea) tablets, which caused her to turn blue and have breathing problems. The vet confirmed she had methaemoglobinaemia, a condition where the blood can't carry enough oxygen. Treatment included methylene blue, oxygen, a blood transfusion, and other supportive care. Thankfully, her condition improved within 16 hours, and she made a full recovery after a few days of additional treatment.
People also search for: dog eating hydroxyurea tablets · greyhound breathing problems · methaemoglobinaemia treatment in dogs
Abstract
A three-year-old female neutered greyhound was presented after ingestion of its owner's hydroxycarbamide (hydroxyurea) tablets. The dog was found to be cyanosed, and methaemoglobinaemia was demonstrated by co-oximetry. Therapy included methylene blue, oxygen, packed red blood cell transfusion, N-acetylcysteine and crystalloid fluids. Methaemoglobinaemia resolved within 16 hours. Granulocyte colony-stimulating factor was administered for five days in an attempt to prevent severe neutropenia. Mild delayed transient myelotoxicity was suspected. The dog made a full recovery.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17850274/