Peer-reviewed veterinary case report
"MitoTea": Geranium robertianum L. decoctions decrease blood glucose levels and improve liver mitochondrial oxidative phosphorylation in diabetic Goto-Kakizaki rats.
- Journal:
- Acta biochimica Polonica
- Year:
- 2010
- Authors:
- Ferreira, Fernanda M et al.
- Affiliation:
- Department of Environment
- Species:
- rodent
Abstract
Several chemical compounds found in plant products have proven to possess beneficial properties, being currently pointed out due to their pharmacological potential in type 2 diabetes mellitus complications. In this context, we studied the effect of Geranium robertianum L. (herb Robert) leaf decoctions in Goto-Kakizaki (GK) rats, a model of type 2 diabetes. Our results showed that oral administration of G. robertianum leaf decoctions over a period of four weeks lowered the plasma glucose levels in diabetic rats. Furthermore, the treatment with G. robertianum extracts improved liver mitochondrial respiratory parameters (state 3, state 4 and FCCP-stimulated respiration) and increased oxidative phosphorylation efficiency.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/21046015/