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Peer-reviewed veterinary case report

Modified Vaccinia Ankara Virus Vaccination Provides Long-Term Protection against Nasal Rabbitpox Virus Challenge.

Journal:
Clinical and vaccine immunology : CVI
Year:
2016
Authors:
Jones, Dorothy I et al.
Affiliation:
Department of Pathology · United States

Abstract

Modified vaccinia Ankara virus (MVA) is a smallpox vaccine candidate. This study was performed to determine if MVA vaccination provides long-term protection against rabbitpox virus (RPXV) challenge, an animal model of smallpox. Two doses of MVA provided 100% protection against a lethal intranasal RPXV challenge administered 9 months after vaccination.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/27146001/