Peer-reviewed veterinary case report
Molecular data of UL24 homolog gene (ORF37) from Brazilian isolates of equine herpesvirus type 1.
- Journal:
- Research in veterinary science
- Year:
- 2012
- Authors:
- Carvalho, R F et al.
- Affiliation:
- Laborató · Brazil
- Species:
- horse
Abstract
Equine herpesvirus type 1 (EHV-1) is associated with abortions, respiratory distress, and neurological disturbances in horses. The ORF37 of EHV-1 encodes a protein homolog to UL24 gene product of human herpesvirus that has been associated with neurovirulence. In the present work, ORF37 PCR fragments derived from two Brazilian EHV-1 isolates, a German isolate and an American reference strain were sequenced and characterized by molecular phylogenetic analysis. This genomic region is highly conserved an allowed to infer genetic distances between EHV-1 strains and other animal herpesvirus.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/21684566/