Peer-reviewed veterinary case report
Molecular testing finds Anaplasmataceae in dogs with ehrlichiosis
By Dagnone, Ana Sílvia et al.·Published in Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria·2009·Departamento de Patologia Veteriná, Brazil·View original on PubMed →
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Original publication title: Molecular diagnosis of Anaplasmataceae organisms in dogs with clinical and microscopical signs of ehrlichiosis.
- Species:
- dog
Plain-English summary
A group of dogs showing signs of ehrlichiosis, like fever and lethargy, were tested for tick-borne infections caused by Anaplasmataceae organisms. Out of 51 dogs, 46 tested positive for these infections using a specialized DNA test, with the most common being E. canis. This study found that PCR testing is the most reliable way to diagnose these infections in dogs. Early detection and treatment can help manage the symptoms and improve recovery chances.
People also search for: dog ehrlichiosis symptoms · how to treat ehrlichiosis in dogs · tick-borne diseases in dogs
Abstract
Ehrlichioses are important emerging zoonotic tick-borne diseases that can affect both animals and humans. Clinical manifestations of ehrlichiosis caused by different members of Anaplasmataceae in dogs are similar to each other and to other diseases showing systemic manifestation. The observation of inclusions in white blood cells and in platelets cannot be used to confirm the Anaplasmataceae etiologic agent of the disease. In this work we assessed the presence of Anaplasmataceae agents in 51 dogs from two different cities (Jaboticabal and Campo Grande) showing clinical and microscopical diagnosis of ehrlichiosis, by using molecular techniques. Anaplasmataceae DNA were amplified in 46/51 (90.2%) of the blood samples; 22 (40%) samples from Jaboticabal and 10 (18.2%) from Campo Grande were positive for E. canis nPCR. Anaplasma platys DNA was amplified in 2 samples from Jaboticabal and in 11 from Campo Grande. Phylogenetic analysis of E. canis and A. platys DNA confirmed the infection agent and showed that PCR is the most reliable method to diagnose ehrlichial infection.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20040204/