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Peer-reviewed veterinary case report

Monoclonal gammopathy in dogs with myeloma and leishmaniasis

By Antognoni, M T et al.·Published in Veterinary research communications·2010·Department of Pathology, Italy·View original on PubMed

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Original publication title: Monoclonal gammopathy associated with multiple myeloma and visceral leishmaniasis in the dog: a comparison of two cases.

Species:
dog

Plain-English summary

A 7-year-old mixed-breed dog was diagnosed with a rare blood condition called monoclonal gammopathy, which can be linked to serious diseases like multiple myeloma and leishmaniasis (a parasitic infection). In one case, the dog had multiple myeloma, while in another, the condition developed three years after the dog was treated for leishmaniasis. Both cases highlight the complexity of diagnosing and treating these serious health issues in dogs. Treatment options would depend on the specific diagnosis, and it's crucial for pet owners to work closely with their veterinarian for the best care.

People also search for: dog blood condition monoclonal gammopathy · dog multiple myeloma treatment · leishmaniasis in dogs symptoms

Abstract

The term monoclonal gammopathy (MG) suggests the presence of clonal immunoglobulins in blood serum that are recognized as narrow spikes in the beta and/or gamma region of the electrophoretic pattern of serum. In the dog, MG is rare and is associated with a heterogeneous group of diseases that include multiple myeloma (the most common source of MG) as well as infectious and chronic inflammatory diseases such as Leishmaniasis. In this paper, two cases of MG are described: the first case is associated with multiple myeloma of monoclonal component type IgA/lambda, with the latter rare in dogs, and the second case involves MG that developed 3 years after an initial diagnosis of Leishmaniasis.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20461463/