Peer-reviewed veterinary case report
Dog with one-eye rapid eye movement linked to possible new seizure
By De Frias, João Miguel et al.·Published in Journal of veterinary internal medicine·2026·The Royal (Dick) School of Veterinary Studies Hospital for Small Animals, United Kingdom·View original on PubMed →
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Original publication title: Monocular ictal nystagmus in a dog: potentially a newly recognized focal seizure phenotype.
- Species:
- dog
Plain-English summary
A 3-year-old male toy Chinese crested dog suddenly became less responsive and developed severe seizures. During the vet's examination, the dog showed unusual eye movements, including rapid movement of the left eye and abnormal positioning of the right eye. Brain imaging revealed multiple lesions in the dog's brain, and tests indicated inflammation. Unfortunately, despite treatment efforts, the dog did not survive. This case highlights a rare type of seizure that caused specific eye movements, which is not commonly seen in dogs.
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Abstract
A 3-year-old, male neutered toy Chinese crested powderpuff dog was presented with an acute onset obtundation that progressed to status epilepticus. On presentation, neurological examination was localized to a right forebrain lesion. Bizarre episodes, consisting of disconjugate nystagmus of the left eye, medial strabismus of the right eye with convergent-retraction movements in both eyes, were recorded. Head magnetic resonance imaging revealed intra-axial multifocal lesions affecting the right fronto-temporal cortices and dorsal paramedian thalamus. Cerebrospinal fluid analysis revealed a marked mononuclear pleocytosis. Electroencephalographic recordings revealed recurrent medium-amplitude interictal isolated spikes, and suspected epileptic spikes alongside with eye movement that were mainly visible in the right hemisphere. The presumptive diagnosis was meningoencephalitis of unknown origin. Despite treatment, the dog died. This is a report of monocular nystagmus with a presumptive epileptic origin in veterinary medicine, a rare clinical sign in human patients.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/41742548/