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Peer-reviewed veterinary case report

MRI shows spinal vein blockage from lymphoma in large dog

By Gilbert, Samantha et al.·Published in Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·2023·Cave Veterinary Specialists, United Kingdom·View original on PubMed

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Original publication title: MRI characteristics of ventral vertebral venous plexus occlusion due to lymphoma in a large breed dog.

Species:
dog
LymphomaBrain & nervesDogs

Plain-English summary

A 9-year-old male neutered Collie was brought in after experiencing painful weakness in his back legs for six days and swollen lymph nodes for three months. An MRI showed that his spinal cord was being compressed due to an enlarged vein in his lower back caused by a rare type of lymphoma. The vet confirmed the diagnosis through a tissue sample, and treatment options would typically include chemotherapy. While the outcome isn't specified, early detection and treatment are crucial for managing lymphoma in dogs.

People also search for: dog back leg weakness · Collie lymphoma symptoms · dog spinal cord compression treatment

Abstract

Intravascular lymphoma is a rare presentation of lymphoma with a predilection to the central nervous system (CNS). A 9-year-old male-neutered Collie presented with a 3-month history of lymphadenopathy and a 6-day history of an acute onset, progressive, painful, symmetrical L4-S3 myelopathy. Magnetic resonance imaging revealed multifocal extradural spinal cord compressions from L3 to L6 secondary to a bilaterally enlarged and occluded ventral vertebral venous plexus (VVVP). Histopathology revealed low-grade lymphoma within the venous plexus in the lumbar vertebral column, tracheobronchial lymph nodes, and tonsils. Intravascular lymphoma should be considered a differential diagnosis for enlarged VVVP causing compression of the spinal cord.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/36305600/