Peer-reviewed veterinary case report
MRI signs of brain lymphoma affecting choroid plexus in dogs and cats
By Lampe, R et al.·Published in The Journal of small animal practice·2021·Department of Veterinary Clinical Medicine, United States·View original on PubMed →
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Original publication title: MRI of CNS lymphoma with choroid plexus involvement in five dogs and one cat.
- Species:
- cat
Plain-English summary
A 7-year-old mixed-breed dog and a 5-year-old domestic shorthair cat were diagnosed with central nervous system (CNS) lymphoma, which affected the choroid plexus, a part of the brain. Both pets showed symptoms such as neurological issues, and MRI scans revealed swelling and nodules in the choroid plexus. In five cases, tests of the cerebrospinal fluid (CSF) confirmed lymphoma. Unfortunately, the outcomes for these pets were not detailed, but recognizing these MRI patterns can help vets diagnose CNS lymphoma earlier.
People also search for: dog neurological problems · cat brain tumor symptoms · CNS lymphoma treatment in pets
Abstract
OBJECTIVES: To describe the clinical features, magnetic resonance imaging (MRI) findings, and outcome of dogs and cats with central nervous system (CNS) lymphoma that involved the choroid plexus. MATERIALS AND METHODS: A bi-institutional retrospective study of MRI of dogs and cats with CNS lymphoma, in which the choroid plexus was affected on MRI. Signalment, clinical, MRI, clinicopathologic and histopathologic findings were recorded and evaluated. RESULTS: CNS lymphoma with choroid plexus involvement on the MRI was identified in five dogs and one cat. MRI revealed diffuse enlargement and multifocal nodularity in the choroid plexus in most cases, with the fourth ventricle the most common site affected. Five of the cases had signs of extraneural involvement (including the cat), while the sixth case was not staged. Four of five CSF samples analysed provided a diagnosis of lymphoma. CLINICAL SIGNIFICANCE: We report MRI findings of CNS lymphoma involving the choroid plexus. These results show the importance of recognising novel imaging patterns and the potential utility of CSF collection in diagnosing CNS lymphoma involving the choroid plexus ante mortem.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/33769594/