Peer-reviewed veterinary case report
Brain metastases from bone cancer in an old English Sheepdog
By Toni, Cristina et al.·Published in Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·2021·Neurology, United Kingdom·View original on PubMed →
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Original publication title: MRI of osteosarcoma metastases in the brain of an old English Sheepdog.
- Species:
- dog
Plain-English summary
A 9-year-old male neutered Old English Sheepdog was brought in because he was acting strangely, had trouble seeing, and seemed to ignore things around him for about 10 days. An MRI of his brain showed multiple unusual spots that turned out to be cancer spread from an osteosarcoma (bone cancer) in his right front leg. Sadly, the dog passed away, and the brain examination confirmed the cancer had spread. This case highlights how osteosarcoma can affect the brain in dogs, which hasn't been widely reported before.
People also search for: dog altered mentation · Old English Sheepdog vision problems · osteosarcoma brain metastases in dogs
Abstract
A 9-year-old, male neutered old English Sheepdog was presented for further investigation of altered mentation, impaired vision, and hemineglect syndrome of 10 days duration. An MRI study of the brain revealed multifocal, contrast-enhancing intra-axial lesions that had a stippled hypointense appearance in all sequences but lacked evidence of a strong signal void on T2* images. Histological examination of the brain postmortem confirmed the lesions were metastases arising from an osteosarcoma, which was later identified in the right humerus. To the authors' knowledge, these MRI characteristics of osteosarcoma metastases in the canine brain have not been previously reported.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/30864172/