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Peer-reviewed veterinary case report

Multicentric T-cell lymphoma presenting as inferior palpebral swelling in a Standardbred mare.

Journal:
Australian veterinary journal
Year:
2012
Authors:
Rendle, D I et al.
Affiliation:
Charles Sturt University · United Kingdom
Species:
horse

Plain-English summary

A 6-year-old Standardbred mare had swelling around her eyes and a sore on her left eye, which led to a diagnosis of multicentric T-cell lymphoma, a type of cancer affecting the immune system. She also showed signs of swollen lymph nodes under her jaw, swelling in her throat, and nasal congestion. Unfortunately, before she could be treated effectively, she developed a serious eye condition related to the use of high doses of steroids. This case highlights that swelling around the eyes can be a sign of lymphoma, even though it's not a common symptom. Ultimately, the treatment did not work, and the mare was euthanized.

Abstract

A 6-year-old Standardbred mare that presented with bilateral palpebral swelling and a left corneal ulcer was diagnosed with a multicentric T-cell lymphoma. Other clinical findings included submandibular lymphadenopathy and oedema, pharyngeal oedema and rhinitis. Prior to euthanasia the horse developed keratomalacia, the onset of which was coincidental with the use of high doses of topical and systemic corticosteroids. Although an unusual presentation, palpebral swelling should be considered as a clinical sign of lymphoma.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/23186090/