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Peer-reviewed veterinary case report

Lumps on a Labrador's paw pads linked to amyloidosis and tumors

By M.P.A. Correia et al.·Published in Arquivo Brasileiro de Medicina Veterinária e Zootecnia·2025·View original on DOAJ

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Original publication title: Multifocal cutaneous nodular amyloidosis associated or not with plasmacytoma in a Labrador dog’s cushions - a case report

Species:
dog

Plain-English summary

An 8-year-old male Labrador was brought in for surgery due to tumor growths on the cushions of his front and back legs. After the surgery, the tissue samples were examined and revealed that he had cutaneous nodular amyloidosis, a rare skin condition, along with a type of tumor called plasmacytoma in some of the growths. Thankfully, the dog was in stable condition before the surgery, and the procedure allowed for a proper diagnosis. The outcome will depend on further treatment and monitoring of his condition.

People also search for: Labrador dog tumor on paw · cutaneous nodular amyloidosis in dogs · plasmacytoma treatment for dogs

Abstract

ABSTRACT Cutaneous nodular amyloidosis is a rare disease in dogs and cats, defined by the accumulation of amyloid deposits in the dermis, which may be associated with extramedullary plasmacytoma. A male Labrador dog, eight years old, had a history of tumor growth in cushions of the right and left thoracic limbs (RTL and LTL, respectively) and right pelvic limb (RPL), had a clinically stable general condition, and it was referred for a surgical procedure. After surgery, the tissue fragments were fixed in 10% buffered formalin and sent for histopathological examination. Microscopically, showed the presence of cutaneous nodular amyloidosis in an LTL and cutaneous nodular amyloidosis associated with plasmacytoma in cushions of the RTL and RPL. Thus, this report is a case of multifocal cutaneous nodular amyloidosis associated or not with plasmacytoma in a Labrador dog’s cushions.

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Original publication on DOAJ: https://doi.org/10.1590/1678-4162-13569