Peer-reviewed veterinary case report
Multifocal brain tumors causing seizures and behavior changes
By Koch, Michael W et al.·Published in Journal of the American Animal Hospital Association·2011·Department of Clinical Studies, United States·View original on PubMed →
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Original publication title: Multifocal oligodendroglioma in three dogs.
- Species:
- dog
Plain-English summary
Three dogs were diagnosed with multifocal oligodendrogliomas, a type of brain tumor, after showing symptoms like seizures and changes in behavior. During their exams, vets noticed issues with coordination and other neurological problems. While one dog's MRI showed brain lesions, another's scan appeared normal. Unfortunately, all three dogs were euthanized due to worsening neurological issues and complications like aspiration pneumonia. This case highlights the importance of considering oligodendrogliomas when dogs present with multiple brain-related symptoms.
People also search for: dog seizures behavior changes · dog brain tumor symptoms · dog neurological problems treatment
Abstract
This report describes the clinical, histopathologic, and imaging findings of multifocal oligodendrogliomas from three canine patients. Clinical history varied but included seizure activity and behavior changes. Neurologic examination abnormalities included ataxia, proprioceptive deficits, cranial nerve deficits, and changes in mentation. MRI in one patient revealed multifocal brain lesions; however, the MRI was normal in another one of the patients. Histopathologic evaluation identified multifocal neoplastic infiltrates in all three patients involving the cerebral cortex, brainstem, and spinal cord, with leptomeningeal extension in two of the three patients. All three patients were euthanized due to progression of their neurologic condition and/or complications due to aspiration pneumonia. Oligodendrogliomas should be considered a differential diagnosis for patients with multifocal brain disease.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21896836/