Peer-reviewed veterinary case report
Skull bone tumor in older large dogs and treatment outcomes
By Dernell, W S et al.·Published in Journal of the American Animal Hospital Association·1998·Department of Veterinary Clinical Sciences, United States·View original on PubMed →
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Original publication title: Multilobular osteochondrosarcoma in 39 dogs: 1979-1993.
- Species:
- dog
Plain-English summary
A group of older large-breed dogs, diagnosed with a type of bone cancer called multilobular osteochondrosarcoma, presented with a fixed mass on their skull. Out of the 39 dogs, 25 underwent surgery to remove the tumor, while others received additional treatments or no treatment at all. Unfortunately, nearly half of the dogs that were treated experienced a return of the tumor, and over half developed metastasis (spread of cancer). Despite these challenges, aggressive treatment can lead to long-term remission for some dogs.
People also search for: dog skull tumor treatment · multilobular osteochondrosarcoma in dogs · large breed dog cancer survival rate
Abstract
Thirty-nine, older, large-breed dogs with multilobular osteochondrosarcoma (MLO) each presented primarily with a fixed mass involving the flat bones of the skull. Twenty-five dogs were treated with surgical resection alone, nine were treated with adjuvant therapy, and five were not treated. Forty-seven percent of dogs treated had local tumor recurrence, and 56% had metastasis. Median time to recurrence, median time to metastasis, and median survival time were 797, 542, and 797 days, respectively. Histological grade, surgical margins, and tumor location affected outcome. Long-term remission can be obtained with aggressive treatment of MLO, although it is locally invasive and moderately metastatic.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/9527424/