Peer-reviewed veterinary case report
Dog tongue melanoma treated with immunotherapy and kinase inhibitors
By Alexander Berry et al.·Published in Veterinary Sciences·2022·Queen’s Veterinary School Hospital, University of Cambridge, Cambridge CB3 0ES, UK, CH·View original on DOAJ →
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Original publication title: Multimodal Treatment of a Canine Lingual Melanoma Using a Combination of Immunotherapy and a Tyrosine Kinase Inhibitors
- Species:
- dog
Plain-English summary
A 9-year-old female Miniature Schnauzer was diagnosed with a malignant melanoma (a type of cancer) on her tongue after a biopsy. The owner chose not to pursue surgery, so the vet started a combination treatment of immunotherapy and tyrosine kinase inhibitors, which are medications that can help fight cancer. Remarkably, the tumor shrank significantly, and the dog maintained a good quality of life. At the time of the report, she had survived for 15 months after her diagnosis, suggesting that this treatment approach could be beneficial for other dogs with similar conditions.
People also search for: dog tongue cancer treatment · Miniature Schnauzer melanoma · immunotherapy for dog cancer
Abstract
A 9-year-old female neutered Miniature Schnauzer was diagnosed with a lingual malignant melanoma on the basis of incisional biopsy and histopathology. The patient was initially given a guarded prognosis of a few months’ survival as surgical treatment options were declined by the owner. In order to control the disease a combination treatment of immunotherapy and tyrosine kinase inhibitors was initiated. The mass showed a marked and sustained reduction in size, whilst preserving quality of life for the patient, with a survival at the time of writing of 15 months since diagnosis. This experience suggests that combination therapy for oral malignant melanoma using immunotherapy and tyrosine kinase inhibitors may be successful in some patients and warrants further investigation.
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Search related cases →Original publication on DOAJ: https://doi.org/10.3390/vetsci9020054