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Peer-reviewed veterinary case report

Dog with multiple skin lumps from malignant testicular Leydig tumor

By Canadas, A et al.·Published in Journal of comparative pathology·2016·Pathology and Immunology Department·View original on PubMed

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Original publication title: Multiple Cutaneous Metastasis of a Malignant Leydig Cell Tumour in a Dog.

Species:
dog

Plain-English summary

An 11-year-old golden retriever was brought to the vet with an enlarged testicle and three skin lumps. Tests showed that these lumps were actually cancerous growths that had spread from a malignant Leydig cell tumor in the testicle. The vet confirmed the diagnosis through special staining techniques that identified the cancer type. Unfortunately, this type of cancer can be aggressive, and treatment options may vary. It's important for pet owners to discuss potential treatments and outcomes with their veterinarian.

People also search for: dog testicular cancer symptoms · golden retriever skin lumps · treatment for dog cancer

Abstract

A testicular Leydig cell tumour associated with metastatic disease is reported in a dog. An enlarged testis and three cutaneous nodules resected from an 11-year-old golden retriever were submitted for histopathological examination. Both testicular and cutaneous lesions showed identical morphological and cytological changes. Immunohistochemical labelling for expression of inhibin-α and calretinin confirmed the Leydig origin of the cutaneous neoplastic population. Based on the morphological and immunohistochemical findings, a final diagnosis of multiple cutaneous metastasis of a malignant testicular Leydig cell tumour was made.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/27392423/