Peer-reviewed veterinary case report
Dog with multiple skin muscle tumors removed and studied
By Aihara, Naoyuki et al.·Published in The Journal of veterinary medical science·2019·School of Veterinary Medicine, Japan·View original on PubMed →
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Original publication title: Multiple cutaneous pleomorphic leiomyosarcoma in a dog.
- Species:
- dog
Plain-English summary
A 12-year-old male dog developed multiple skin lumps on 15 different areas of his body over a year and a half. The lumps were surgically removed and examined, revealing they were tumors made up of abnormal muscle cells. The diagnosis was multiple cutaneous pleomorphic leiomyosarcoma, a type of cancer affecting the skin. Treatment involved surgery to remove the masses, and while the outcome isn't specified, surgical removal is often the first step in managing such tumors.
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Abstract
A male dog developed multiple cutaneous masses at 15 different sites between the ages of 11.5 and 13-years. The masses were surgically removed and histopathologically examined. In gross appearance, the cut surfaces of the masses were white with partially red areas. Microscopy revealed that the tumors were located at the dermis and were composed of spindle cells and pleomorphic cells with abundant eosinophilic cytoplasm, accompanying giant cells. These cells were occasionally arranged in bundles with minimal stromal collagen. Immunohistochemical analysis revealed that the neoplastic cells were strongly positive for vimentin, partially positive for smooth muscle actin and desmin, and negative for cytokeratin. Based on these pathological findings, the tumor was diagnosed as multiple cutaneous pleomorphic leiomyosarcoma.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/31511446/