Peer-reviewed veterinary case report
Crossbred dog with multiple endocrine tumors causing drinking
By Walker, M C et al.·Published in The Journal of small animal practice·2000·Department of Veterinary Clinical Sciences·View original on PubMed →
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Original publication title: Multiple endocrine neoplasia type 1 in a crossbred dog.
- Species:
- dog
Plain-English summary
A 12-year-old male crossbred dog was brought in due to increased thirst and urination for the past four months, along with a swollen abdomen and skin issues. Tests showed high calcium levels and problems with hormone regulation, leading to the discovery of a growth on the parathyroid gland. The vet surgically removed the growth, which was confirmed to be a benign tumor. The dog was also treated for a related hormone condition with a medication called mitotane for 14 months, but unfortunately, he was later euthanized due to an unrelated health issue.
People also search for: dog increased thirst and urination · crossbred dog parathyroid tumor treatment · mitotane for dog hormone problems
Abstract
Multiple endocrine neoplasia type 1 was diagnosed in a 12-year-old male crossbred dog. Relevant history included polyuria and polydipsia of four months' duration. Physical examination revealed abdominal enlargement, seborrhoea and polypnoea. Diagnostic tests indicated hypercalcaemia, elevated serum alkaline phosphatase and alanine aminotransferase, an exaggerated response to adrenocorticotropic stimulation of the adrenal gland, lack of cortisol suppression with a low dose dexamethasone suppression test and suppression of cortisol secretion with a high dose dexamethasone test. An enlarged right parathyroid gland was removed surgically and confirmed histopathologically to be a parathyroid adenoma. The pituitary-dependent hyperadrenocorticism was treated successfully with mitotane for 14 months before the patient was euthanased for an unrelated problem.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/10701189/